Location History:
- Natick, MA (US) (1997 - 2000)
- Arlington, MA (US) (1997 - 2002)
Company Filing History:
Years Active: 1997-2002
Title: Innovations of Shyam K Singh in HIV Research
Introduction
Shyam K Singh is a notable inventor based in Arlington, MA (US), recognized for his significant contributions to medical research, particularly in the field of HIV treatment. With a total of four patents to his name, Singh has made strides in developing compounds that can potentially inhibit HIV infectivity.
Latest Patents
One of Singh's latest patents involves a compound for inhibiting HIV infectivity. This invention focuses on the discovery that condensation polymers of an aldehyde and aromatic sulfonic acids, such as formaldehyde naphthalenesulfonic acid condensation polymers, can effectively abrogate HIV gp120 binding to CD4. This has been demonstrated through CD4/gp120 binding assays. In addition to inhibiting gp120 binding, these compounds have shown the ability to inhibit HIV-induced syncytia formation and the infectivity of CD+ cells. Importantly, the use of this compound has been found to be non-cytotoxic and does not inhibit antigen-induced T lymphocyte proliferation. Based on these findings, these compounds hold promise as therapeutic agents for the treatment of acquired immunodeficiency syndrome (AIDS), AIDS-related complex (ARC), AIDS-related dementia, and non-symptomatic HIV infection. Furthermore, they can also be utilized to treat blood preparations.
Career Highlights
Shyam K Singh is currently associated with Procept Corporation, where he continues to innovate and contribute to the field of medical research. His work has garnered attention for its potential impact on HIV treatment and patient care.
Collaborations
Singh has collaborated with notable colleagues, including Raymond J Patch and Peter V Pallai, who share his commitment to advancing research in HIV and related fields.
Conclusion
Shyam K Singh's innovative work in developing compounds to inhibit HIV infectivity showcases his dedication to improving health outcomes for individuals affected by HIV. His contributions are paving the way for new therapeutic options in the fight against this disease.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.