Location History:
- Kobe-shi, Hyogo, JP (2003 - 2009)
- Nishi-ku, Kobe-shi, Hyogo JP (2009)
- Nishi-ku, Kobe-shi, Hyogo, JP (2003 - 2010)
Company Filing History:
Years Active: 2003-2010
Title: Shunichi Shiozawa: Innovator in Rheumatoid Arthritis Research
Introduction
Shunichi Shiozawa is a notable inventor based in Hyogo, Japan. He has made significant contributions to the field of medical research, particularly in the diagnosis and treatment of rheumatoid arthritis. With a total of 6 patents to his name, Shiozawa's work has the potential to impact the lives of many patients suffering from this condition.
Latest Patents
Shiozawa's latest patents focus on innovative methods for diagnosing rheumatoid arthritis. One of his key inventions involves analyzing DNA methylation in the region upstream from the translation initiation point of the rheumatoid arthritis-associated gene DR3. His research revealed that allele-specific methylation occurs in a CpG sequence located approximately -380 to -180 bp upstream from the ATG of the gene DR3. Furthermore, he discovered that while the CpG sequences in healthy individuals are unmethylated, both methylated and unmethylated sequences are present in the genes DR3 of rheumatoid arthritis patients.
Another significant patent identifies a gene on Human Chromosome 8 as a susceptibility gene for rheumatoid arthritis. This gene encodes a protein with a specific amino acid sequence, which includes a mutation where glycine is inserted as the 269th amino acid. Shiozawa's work has led to the development of a method for accurately evaluating the onset or possibility of rheumatoid arthritis using this mutation.
Career Highlights
Throughout his career, Shunichi Shiozawa has been dedicated to advancing medical research and improving diagnostic methods for rheumatoid arthritis. His innovative approaches have garnered attention in the scientific community and have the potential to lead to better treatment options for patients.
Collaborations
Shiozawa has collaborated with notable colleagues, including Koichiro Komai and Kayo Osawa. These partnerships have contributed to the advancement of his research and the development of his patents.
Conclusion
Shunichi Shiozawa's contributions to the field of rheumatoid arthritis research exemplify the impact of innovation in medicine. His patents not only enhance our understanding of the disease but also pave the way for improved diagnostic and treatment methods.