Company Filing History:
Years Active: 2020
Title: Shuangjie Shu: Innovator in Chiral Ligand Synthesis
Introduction: Shuangjie Shu is an accomplished inventor based in Shanghai, China. His work primarily focuses on synthesizing novel chemical compounds that have significant implications in the pharmaceutical industry. With a patented method that showcases innovative techniques, Shu continues to contribute to advancements in chemical research.
Latest Patents: Shu holds a patent for a method for synthesizing a novel chiral ligand, metal chelate, a variety of non-natural amino acids, Maraviroc, and a key intermediate thereof. This significant invention involves using (R)-2-methyl proline as a raw material to produce (S)-β-amino acid through asymmetric resolution with a nickel chelate. The synthesis of Maraviroc uses (S)-3-amino-3-phenylpropionic acid as a key intermediate, achieving a high yield with an optical purity exceeding 98.2%. The method is characterized by readily available materials, mild synthetic conditions, and ease of control.
Career Highlights: Shuangjie Shu is affiliated with the Chinese Academy of Sciences, where he actively engages in groundbreaking research. His contributions to the field of chiral chemistry highlight his expertise and dedication to creating innovative solutions for complex chemical synthesis.
Collaborations: Throughout his career, Shu has had the opportunity to work alongside esteemed colleagues such as Hong Tao Liu and Jiang Wang. These collaborations have enriched his research and facilitated the advancement of innovative projects within the scientific community.
Conclusion: As a pioneering inventor, Shuangjie Shu exemplifies the spirit of innovation in the field of chemistry. His patented method for synthesizing chiral ligands and amino acids demonstrates the potential for future advancements in pharmaceuticals, driven by rigorous research and collaboration.