Company Filing History:
Years Active: 2011-2014
Title: Shree R Singh: Innovator in Biotechnology
Introduction
Shree R Singh is a notable inventor based in Montgomery, AL (US). She has made significant contributions to the field of biotechnology, particularly in the development of innovative methods for detecting nucleic acid sequences. With a total of 3 patents to her name, her work has the potential to impact various medical applications.
Latest Patents
One of her latest patents is focused on a DNA biochip and methods of use. This invention concerns materials and methods for detecting nucleic acid sequences. A key aspect of the invention involves a silicon-based biochip that comprises nucleic acid immobilized on its surface. In one embodiment, the silicon features microcavities, allowing for the immobilization of nucleic acids to be assayed for the presence of target nucleic acid sequences. The invention utilizes oligonucleotide probes that are substantially complementary to the target nucleic acid sequences for detection. If the nucleic acid used for detection hybridizes with a target sequence, the hybridized sequences can be detected either directly or indirectly. The oligonucleotide probe can be labeled with a detectable label, such as a fluorescent molecule. Additionally, the invention includes methods for detecting target nucleic acids using the silicon-based biochip.
Another significant patent involves anti-respiratory syncytial virus (RSV) peptide functionalized gold nanoparticles. This invention focuses on an anti-RSV peptide derived from a segment of the human RSV fusion protein precursor F0. The method provided allows for the attachment of peptides to carboxylated gold particles, creating additional anti-RSV agents that can prevent or inhibit infections by RSV and related viruses, including HIV.
Career Highlights
Shree R Singh has worked at prominent institutions such as Alabama State University and the University of South Florida. Her work in these organizations has contributed to her expertise in biotechnology and innovation.
Collaborations
Some of her notable coworkers include Arun Babu Kumar and Ashok Kumar. Their collaborative efforts have further advanced the research and development of her patented technologies.
Conclusion
Shree R Singh is a pioneering inventor whose work in biotechnology has led to significant advancements in the detection of nucleic acids and the development of anti-viral agents. Her contributions continue to influence the field and hold promise for future medical applications.