Shogo Matoba

Title: Shogo Matoba: Innovator in Somatic Cell Nuclear Transfer

Introduction

Shogo Matoba is a prominent inventor based in Brookline, MA (US). He has made significant contributions to the field of biotechnology, particularly in the area of somatic cell nuclear transfer (SCNT). His innovative work has led to the development of methods that enhance the efficiency of SCNT, which is crucial for advancements in regenerative medicine and genetic research.

Latest Patents

Shogo Matoba holds 2 patents that focus on improving SCNT efficiency. His latest patents include methods and compositions aimed at increasing SCNT efficiency by removing histone H3-lysine trimethylation. The inventions provide insights into how trimethylation of Histone H3-Lysine 9 (H3K9me3) in reprogramming resistant regions (RRRs) can hinder effective somatic cell nuclear reprogramming. By targeting the demethylase Kdm4 family and inhibiting histone methyltransferases Suv39h1 and Suv39h2, these methods aim to enhance the efficacy of SCNT.

Career Highlights

Shogo Matoba is affiliated with the Children's Medical Center Corporation, where he continues to push the boundaries of scientific research. His work is instrumental in the development of new techniques that could lead to breakthroughs in the production of nuclear transfer embryonic stem cells (ntESC) and transgenic organisms.

Collaborations

Shogo Matoba collaborates with Yi Zhang, a fellow researcher, to further explore the complexities of somatic cell nuclear transfer and its applications in medicine.

Conclusion

Shogo Matoba's innovative contributions to the field of somatic cell nuclear transfer highlight his role as a leading inventor in biotechnology. His work not only advances scientific understanding but also paves the way for future developments in regenerative medicine.