This inventor holds 1 USPTO granted patent. Top assignees: Ordos Clinical Medical College of Inner Mongolia. Medical University, Peking University. Active years: 2026.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 1 
1 out of 663 
Years Active: 2026
Title: Shiyuan Yang: Innovator in Fluorescent Contrast Agents
Introduction
Shiyuan Yang is a prominent inventor based in Beijing, China. He has made significant contributions to the field of biomedical materials, particularly through his innovative work on fluorescent contrast agents. His research focuses on enhancing diagnostic techniques for cancer, specifically lymph node metastasis.
Latest Patents
Shiyuan Yang holds a patent for a fluorescent contrast agent with a targeting function, titled "Fluorescent contrast agent with targeting function, and preparation method and use thereof." This invention provides a novel fluorescent contrast agent, known as MR780 NPs, which can specifically bind to CD206 on the surface of tumor-associated macrophages (TAMs). The MR780 NPs accumulate in lymph nodes affected by tumor cells and undergo an oxidation-reduction reaction in the tumor microenvironment, triggering a fluorescence signal. This innovative agent does not accumulate in normal lymph nodes, making it a valuable tool for diagnosing lymph node metastasis (LNM) in breast cancer. It aids in preoperative evaluation, assists in clinical tumor staging, and facilitates accurate surgical resection through intraoperative fluorescence navigation.
Career Highlights
Shiyuan Yang has worked at prestigious institutions, including Peking University and the Ordos Clinical Medical College of Inner Mongolia Medical University. His experience in these organizations has allowed him to advance his research and contribute to the scientific community.
Collaborations
Some of his notable coworkers include Shumin Wang and Xiaolong Liang. Their collaborative efforts have furthered the development of innovative solutions in the field of biomedical materials.
Conclusion
Shiyuan Yang's work in developing targeted fluorescent contrast agents represents a significant advancement in cancer diagnostics. His contributions are poised to enhance the accuracy of tumor staging and surgical planning, ultimately improving patient outcomes.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile