Company Filing History:
4 out of 281 
3 out of 118 
1 out of 1,440 
Years Active: 1996-2004
Title: Shiping Xie: Innovator in Camptothecin Derivatives
Introduction
Shiping Xie is a notable inventor based in Cary, NC (US), recognized for his contributions to the field of pharmaceuticals, particularly in the development of camptothecin derivatives. He holds a total of 10 patents, showcasing his innovative approach to medicinal chemistry.
Latest Patents
One of his latest patents is titled "Preparation of a camptothecin derivative by intramolecular cyclisation." This invention relates to a method for preparing camptothecin and camptothecin-like compounds, along with novel intermediates used in this preparation. The process involves cyclising a specific compound to obtain a camptothecin derivative known by the chemical name “7-(4-methylpiperazino-methylene)-10,11-ethylenedioxy-20(R,S)-camptothecin.” The method also includes options for resolving enantiomers and converting the resulting compound into a physiologically acceptable salt or solvate.
Career Highlights
Throughout his career, Shiping Xie has worked with prominent companies such as Glaxo Wellcome Inc. and Osi Pharmaceuticals, Inc. His experience in these organizations has significantly contributed to his expertise in pharmaceutical innovations.
Collaborations
Shiping Xie has collaborated with notable colleagues, including Francis Gerard Fang and Edward McDonald Huie. These partnerships have likely enhanced his research and development efforts in the field.
Conclusion
Shiping Xie's work in the preparation of camptothecin derivatives exemplifies his innovative spirit and dedication to advancing pharmaceutical science. His contributions continue to impact the field positively.