Hercules, CA, United States of America

Shing Chang


Average Co-Inventor Count = 1.6

ph-index = 9

Forward Citations = 132(Granted Patents)


Location History:

  • Hercules, CA (US) (1984 - 1991)
  • Oakland, CA (US) (1989 - 1991)

Company Filing History:


Years Active: 1984-1991

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13 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Inventor Shing Chang

Introduction

Shing Chang, an accomplished inventor based in Hercules, California, has made significant contributions to the field of biotechnology with a total of 13 patents to his name. His work primarily focuses on methods and systems that enhance protein production, which has critical implications in various biotechnological applications.

Latest Patents

Among his most recent innovations are two impactful patents. The first is for a Bacterial Methionine N-terminal Peptidase, which describes a novel method for obtaining N-terminal methionine-free proteins. This method employs an enzyme known as E. coli methionine aminopeptidase and can be utilized both in vitro and in vivo. For in vivo applications, plasmid-borne DNA encoding this peptidase is transformed into bacterial hosts, enabling the production of the desired proteins.

The second patent revolves around Modified Signal Peptides, derived from wild-type signal peptides capable of forming membrane-bound lipoproteins. This invention outlines methods for producing these modified signal peptides as well as the DNA sequences that encode them. This technology is particularly useful for enhancing the secretion of heterologous gene products from transformed host organisms. Additionally, it presents a method for producing recombinant DNA sequences in vivo.

Career Highlights

Shing Chang has spent a significant portion of his career working at Cetus Corporation, where he has been able to leverage his expertise in protein engineering and biotechnology to develop groundbreaking innovations. His contributions have played a pivotal role in advancing the field and improving production methods for various bioproducts.

Collaborations

Throughout his career, Chang has collaborated with several notable individuals, including Hing C Wong and Arie Ben-Bassat. These collaborations have further enriched his work, allowing for the pooling of knowledge and expertise to drive innovation in biotechnology.

Conclusion

With a proven track record of innovation and collaboration, Shing Chang continues to be a significant figure in the realm of biotechnology. His patents not only reflect his ingenuity but also contribute to the advancement of science and technology in the field, demonstrating the transformative power of innovative thinking.

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