Company Filing History:
Years Active: 1999-2005
Title: The Innovations of Shin Yonehara
Introduction
Shin Yonehara is a prominent inventor based in Tokyo-to, Japan. He has made significant contributions to the field of biotechnology, particularly in the area of DNA coding for human cell surface antigens. With a total of 3 patents to his name, Yonehara's work has implications for understanding cell apoptosis and related medical applications.
Latest Patents
One of Yonehara's latest patents focuses on DNA coding for human cell surface antigens, specifically the Fas antigen. This invention includes DNAs coding for the Fas antigen, vectors for expressing these DNAs, and transformants transfected with the said vector. The Fas antigen is a polypeptide found on the surfaces of various cells and plays a crucial role in the process of apoptosis. The isolated Fas cDNA has an open reading frame capable of encoding a protein consisting of 335 amino acids. The mature Fas antigen itself is a protein made up of 319 amino acids, with a calculated molecular weight of approximately 36,000. It comprises an extracellular domain of 157 amino acids, a membrane-spanning domain of 17 amino acids, and a cytoplasmic domain of 145 amino acids.
Career Highlights
Shin Yonehara is affiliated with the Osaka Bioscience Institute, where he conducts his research and development activities. His work has been instrumental in advancing the understanding of cell surface antigens and their roles in cellular processes.
Collaborations
Yonehara has collaborated with notable colleagues in his field, including Shigekazu Nagata and Naoto Itoh. These collaborations have further enriched his research and contributed to the scientific community's knowledge of cell biology.
Conclusion
Shin Yonehara's innovative work in DNA coding for human cell surface antigens highlights his significant contributions to biotechnology. His patents and collaborations continue to influence the field and pave the way for future advancements in medical science.