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Title: The Innovative Contributions of Shin-Tai Chen
Introduction
Shin-Tai Chen is a notable inventor based in San Diego, CA. He has made significant contributions to the field of biotechnology, particularly in the development of inducible expression systems. With a total of 3 patents to his name, Chen's work has advanced the understanding and application of polypeptide expression in eukaryotic cells.
Latest Patents
Chen's latest patents focus on an inducible expression system that features compositions and methods for the controlled expression of polypeptides. This system is particularly relevant for polypeptides that are normally cytotoxic to the host cells in which they are expressed. The invention involves a nucleotide sequence encoding a polypeptide linked to an inducible promoter, which is regulated by a multi-chimeric transactivating factor. This innovative approach allows for the transcription of the nucleotide sequence to be activated under specific conditions, making it especially useful for the expression of cytotoxic proteins like VSV G for the production of pseudotyped retroviral vectors.
Career Highlights
Throughout his career, Chen has worked with prestigious institutions such as the University of California and City of Hope. His research has contributed to advancements in biotechnology and has had a lasting impact on the field.
Collaborations
Some of Chen's notable coworkers include Jiing-Kuan Yee and Theodore Friedmann. Their collaborative efforts have furthered the research and development of innovative biotechnological solutions.
Conclusion
Shin-Tai Chen's contributions to the field of biotechnology through his patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of new technologies in the industry.