This inventor holds 1 USPTO granted patent. Top assignee: Other. Active years: 2019.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 834,513 Years Active: 2019
Title: Shijie Huang: Innovator in Ribosome Detection Technologies
Introduction
Shijie Huang is a notable inventor based in Albuquerque, NM (US). He has made significant contributions to the field of biotechnology, particularly in the detection of ribosome inhibition. His innovative work has the potential to advance our understanding of cellular processes and improve various applications in medical research.
Latest Patents
Huang holds a patent titled "System and methods for detecting ribosome inhibition." This patent describes a genetically modified cell designed to detect ribosome inhibition within the cell. The genetically modified cell includes an aminoglycoside-sensitive orthogonal 16S rRNA (O-16S) coding region, which features a mutated anti-Shine-Dalgarno (O-ASD) sequence. Additionally, it incorporates a repressor/operator system and a polynucleotide encoding a detectable reporter under the transcriptional control of the repressor/operator system. The repressor/operator system consists of a coding region that encodes a transcriptional regulator, which has an orthogonal SD (O-SD) sequence complementary to the 16S rRNA O-ASD sequence. The operator sequence, which can be repressed by the transcriptional regulator, is operably linked to the polynucleotide encoding a detectable reporter. This innovative approach offers a new method for studying ribosome function and inhibition.
Career Highlights
Throughout his career, Shijie Huang has focused on the intersection of genetics and cellular biology. His work has led to advancements in understanding how ribosomes function and how their inhibition can be detected. Huang's research is crucial for developing new therapeutic strategies and enhancing our knowledge of cellular mechanisms.
Collaborations
Huang collaborates with Charles Melancon, contributing to the advancement of their shared research interests. Their partnership exemplifies the importance of teamwork in scientific innovation.
Conclusion
Shijie Huang's contributions to the field of ribosome detection represent a significant advancement in biotechnology. His patented methods provide valuable tools for researchers and hold promise for future applications in medical science.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile