Shigeyoshi Itohara

Title: Shigeyoshi Itohara: Innovator in Ephrin-Eph Receptor Signaling

Introduction

Shigeyoshi Itohara is a prominent inventor based in Saitama, Japan. He has made significant contributions to the field of neuroscience through his innovative research and inventions. With a total of 2 patents, Itohara's work focuses on the regulation of ephrin-Eph receptor signaling mechanisms.

Latest Patents

His latest patents include a regulator of ephrin-Eph receptor signaling and a mouse model exhibiting abnormal ephrin-Eph receptor signaling mechanisms. The first patent aims to provide an agent for regulating axon extension during neurogenesis by modulating ephrin-Eph receptor signaling. This invention also introduces a miffy (mfy) mouse derived from a B6 strain, which displays an autosomal recessive inheritance of an abnormal walking trait characterized by a hopping gait and synchronized limb movement due to a mutation in the α-chimerin gene. The second patent involves a prion gene modified mouse that exhibits heart anomalies. This invention outlines a method for detecting aberrant animal-derived prion genes by introducing a prion gene into a mouse and observing the resulting heart anomalies.

Career Highlights

Shigeyoshi Itohara is affiliated with Riken Corporation, a leading research institution in Japan. His work has significantly advanced the understanding of ephrin-Eph receptor signaling and its implications in neurodevelopment and prion diseases.

Collaborations

Throughout his career, Itohara has collaborated with notable researchers, including Ryosuke Takahashi and Takuji Iwasato. These collaborations have further enriched his research and contributed to the scientific community.

Conclusion

Shigeyoshi Itohara's innovative work in the field of ephrin-Eph receptor signaling has led to important advancements in neuroscience. His patents reflect a commitment to understanding complex biological mechanisms and their potential applications in medicine.