Shigeru Aoki

Title: **Shigeru Aoki: A Pioneer in Benzimidazole Compound Stabilization**

Introduction

Shigeru Aoki, an innovative inventor based in Gifu, Japan, is renowned for his contributions in the field of pharmaceutical formulations, particularly concerning benzimidazole compounds. With three patents to his name, Aoki's work emphasizes his commitment to enhancing drug stability and efficacy.

Latest Patents

Aoki's recent patents showcase his expertise in stabilizing benzimidazole compounds. One key patent revolves around methods for stabilizing an oral solid formulation containing these compounds or their physiologically acceptable salts. This invention outlines a process that incorporates crospovidone and sodium or potassium hydroxide, thereby enhancing the stability of the benzimidazole-based formulation.

Another significant patent describes a peroral preparation designed for acid-unstable compounds. This innovative approach includes a specialized core containing the acid-unstable compound, coated with a first layer of a hardly water-soluble, film-forming material and fine particles of an insoluble substance. The addition of a second layer featuring an enteric film further protects the delicate compound, ensuring better delivery and efficacy in the body.

Career Highlights

Throughout his career, Shigeru Aoki has played pivotal roles in renowned companies such as Eisai Company, Limited, and Eisai R&D Management Co., Ltd. His work in these organizations has significantly influenced the development of pharmaceutical solutions aimed at improving patient outcomes.

Collaborations

Aoki has collaborated with notable colleagues in the industry, including Keizo Uesugi and Shigeru Sakashita. These collaborations have fostered a creative environment leading to groundbreaking developments in pharmaceutical formulations.

Conclusion

Shigeru Aoki's innovative approach to stabilizing benzimidazole compounds positions him as a significant figure in pharmaceutical research and development. His patents reflect a dedication to improving drug formulations, benefitting both the industry and patients worldwide. Aoki's contributions will undoubtedly inspire future advancements in the field of pharmaceuticals.