Sheldon C Engelhorn

Title: Sheldon C Engelhorn: Innovator in Monoclonal Antibody Purification

Introduction

Sheldon C Engelhorn is a notable inventor based in San Pablo, CA (US). He has made significant contributions to the field of biotechnology, particularly in the purification of monoclonal antibodies. His innovative approach has the potential to enhance the efficiency of antibody analysis and preparation.

Latest Patents

Engelhorn holds a patent for the "Use of hydroxylapatite for the analysis and preparation of purified." This novel method discloses a technique for purifying monoclonal antibodies from antibodies of the same isotype but differing light chain composition. These antibodies are often present in the fluids where such antibodies are generated. The method involves placing the mixture in a hydroxylapatite chromatography column and eluting it with a buffer solution in a concentration gradient. With appropriate optimization of system parameters, effective separation of antibodies for both analytical and preparative purposes is achieved.

Career Highlights

Sheldon C Engelhorn is associated with Bio-Rad Laboratories, Inc., a leading company in the life sciences industry. His work at Bio-Rad has allowed him to focus on innovative solutions that address complex challenges in antibody purification.

Collaborations

Engelhorn has collaborated with notable colleagues, including Hector Juarez-Salinas and Gary S Ott. These collaborations have contributed to the advancement of research and development in the field of biotechnology.

Conclusion

Sheldon C Engelhorn's contributions to monoclonal antibody purification exemplify the impact of innovation in biotechnology. His patented method represents a significant advancement in the field, showcasing his dedication to improving scientific processes.