Company Filing History:
6 out of 4,442 
2 out of 82 Years Active: 1992-2006
Title: Innovations of Sheila P Little
Introduction
Sheila P Little is a prominent inventor based in Indianapolis, IN (US). She has made significant contributions to the field of biomedical research, particularly in the study of Alzheimer's disease and other neurological disorders. With a total of seven patents to her name, her work has the potential to impact the development of new therapeutic strategies.
Latest Patents
One of her latest patents focuses on a novel β-secretase and the modulation of β-secretase activity. This invention involves a method of partially purifying this novel β-secretase and its application in assays designed to screen for potential drug candidates against Alzheimer's disease and other neurological diseases. The novel β-secretase has an estimated molecular weight of about 32-39 kDa or 22-26 kDa in HEK293 cell membrane extracts and human brain samples, respectively. This was calculated from radiation inactivation analysis, and it has a pH optimum at approximately pH 6.5-7.0.
Career Highlights
Throughout her career, Sheila has worked with notable companies such as Eli Lilly and Company and Scios Inc. Her experience in these organizations has contributed to her expertise in the field of drug development and neurological research.
Collaborations
Sheila has collaborated with esteemed colleagues, including Edward Marion Johnstone and Nils U Bang. These partnerships have further enriched her research and innovation efforts.
Conclusion
Sheila P Little's contributions to the field of biomedical research, particularly through her patents related to β-secretase, highlight her role as an influential inventor. Her work continues to pave the way for advancements in the treatment of neurological diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.