Company Filing History:
Years Active: 2000
Title: Innovations by Sharad Murdandi in Local Anesthesia
Introduction
Sharad Murdandi is an accomplished inventor based in Groton, CT (US). He has made significant contributions to the field of anesthetics, particularly through his innovative patent that enhances the efficacy of local anesthesia.
Latest Patents
Murdandi holds a patent for "Sustained-release liposomal anesthetic compositions." This invention provides a method for obtaining local anesthetics encapsulated in liposomes, such as multivesicular liposomes, with high encapsulation efficiency and slow release in vivo. When the encapsulated anesthetic is administered as a single intracutaneous dose, the duration of anesthesia and half-life of the drug at the local injection site is increased compared to the injection of unencapsulated anesthetic. The maximum tolerated dose of the encapsulated anesthetic is also markedly increased in the liposomal formulation over the injection of unencapsulated anesthetic. These results demonstrate that the liposomal formulation of local anesthetic is useful for sustained local infiltration and nerve block anesthesia.
Career Highlights
Sharad Murdandi is associated with Skye Pharma, Inc., where he continues to develop innovative solutions in the field of anesthetics. His work has the potential to significantly improve patient outcomes in medical procedures requiring local anesthesia.
Collaborations
Murdandi has collaborated with notable colleagues, including Sinil Kim and Taehee Kim, to advance his research and innovations in anesthetic formulations.
Conclusion
Sharad Murdandi's contributions to the field of local anesthesia through his patented innovations highlight the importance of research and development in improving medical practices. His work exemplifies the potential for enhanced patient care through innovative solutions.