Shaofeng Xie

Title: The Innovations of Shaofeng Xie

Introduction

Shaofeng Xie is an accomplished inventor based in Rancho Santa Margarita, California. He has made significant contributions to the field of pharmaceuticals, particularly in the development of compositions that enhance the efficacy of L-leucovorin. His innovative work has led to the creation of a patent that addresses important aspects of drug formulation.

Latest Patents

Shaofeng Xie holds a patent for "Pharmaceutical compositions comprising L-leucovorin." This patent describes compositions that utilize a calcium salt of L-leucovorin, which can achieve higher concentrations than those made with racemic leucovorin. The compositions can be prepared to form stable aqueous solutions with a near physiological pH, specifically between 6 and 8. Notably, these formulations may be substantially free of D-leucovorin and can be prepared without the use of EDTA or with minimal amounts of it. The preparation process involves sonicating a mixture of the solid calcium salt of L-leucovorin and water, ensuring that the resulting solution remains stable and effective for injection.

Career Highlights

Shaofeng Xie is currently associated with Spectrum Pharmaceuticals, Inc., where he continues to advance his research and development efforts. His work has been pivotal in enhancing the pharmaceutical applications of L-leucovorin, contributing to improved treatment options in the medical field.

Collaborations

Shaofeng has collaborated with notable colleagues, including Pramod Kumar Gupta and Bahman Shimiaei. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas in pharmaceutical research.

Conclusion

Shaofeng Xie's contributions to pharmaceutical compositions demonstrate his commitment to advancing medical science. His innovative patent work and collaborations highlight the importance of teamwork in achieving breakthroughs in drug formulation.