Shane Barry Robinson

Shane Barry Robinson is a notable inventor based in Midleton, Ireland. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of improved processes for drug preparation. With a total of 2 patents, Robinson's work has the potential to impact the pharmaceutical industry positively.

Latest Patents

One of Robinson's latest patents is focused on a simplified procedure for the preparation of darunavir. This invention relates to an improved process for preparing [(1S,2R)-3-[[(4-aminophenyl)-sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)-propyl]-carbamic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester, known under its International Nonproprietary Name (INN) as darunavir. The process involves reacting carbonic acid 2,5-dioxo-1-pyrrolidinyl [(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]ester with 4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)-benzenesulfonamide in ethanol as a solvent. This innovative method allows for darunavir to be isolated immediately in its ethanolate form, which is the marketed form of darunavir under the tradename Prezista™.

Career Highlights

Shane Barry Robinson is currently employed at Janssen Sciences Ireland Unlimited Company, where he continues to advance his research and development efforts in pharmaceutical innovations. His work is characterized by a commitment to improving drug preparation processes, which can lead to more efficient and effective treatments.

Collaborations

Robinson collaborates with esteemed colleagues, including Alfred Elisabeth Stappers and Yolande Lydia Lang, who contribute to his research endeavors. Their combined expertise enhances the innovative potential of their projects.

Conclusion

Shane Barry Robinson is a prominent figure in pharmaceutical chemistry, with a focus on improving drug preparation processes. His contributions, particularly in the development of darunavir,