Company Filing History:
Years Active: 2014-2025
Title: **Shan Cen: Innovator in Antiviral Research**
Introduction
Shan Cen is a notable inventor based in Beijing, China, recognized for his contributions to antiviral drug development. With two existing patents, he has made significant advancements in the fight against viral infections, particularly Ebola and HIV.
Latest Patents
Shan Cen's latest patents showcase groundbreaking research in antiviral compounds. The first patent, titled "Use of berbamine dihydrochloride in preparation of Ebola virus inhibitor," details the use of berbamine dihydrochloride as an effective inhibitor of the Ebola virus. This invention identifies the primed glycoprotein of the Ebola virus as a target site, and highlights the compound's ability to bind specifically to this protein, significantly inhibiting virus entry. A remarkable finding is that the half-maximum effect concentration (EC50) of berbamine dihydrochloride against the Ebola virus is 0.49 µM, demonstrating its potent inhibitory effect.
The second patent, "Group of amino substituted benzoyl derivatives and their preparation and their use," outlines a series of derivatives designed to combat viral replication. Focusing on the target point of hA3G/Vif, this research proves that 3-amino benzoyl derivatives not only demonstrate combined activity for hA3G/Vif but also possess the capability to inhibit viral replication. This work provides a promising solution to HIV drug resistance, paving the way for a novel and more efficient clinical antiviral drug.
Career Highlights
Throughout his career, Shan Cen has been associated with prestigious research institutions, including the Institute of Medicinal Biotechnology and the Chinese Academy of Medical Sciences. His work at these institutions has been pivotal in advancing antiviral therapies, making him a key figure in this field of research.
Collaborations
Shan Cen is known to have collaborated with esteemed colleagues such as Jian-Dong Jiang and Liyan Yu. Their combined expertise has contributed to the progress and success of numerous research endeavors aimed at developing innovative antiviral treatments.
Conclusion
Shan Cen has established himself as a prominent inventor in the realm of antiviral research. His patents not only reflect his innovative spirit but also highlight his commitment to addressing some of the most pressing issues in infectious disease treatment. With ongoing collaborations and groundbreaking inventions, he continues to make strides towards advancing public health and combating viral infections.