Company Filing History:
Years Active: 2005
Title: Shahul Nilar: Innovator in Polymerase Inhibition
Introduction
Shahul Nilar is a notable inventor based in Irvine, CA. He has made significant contributions to the field of biotechnology, particularly in the development of polymerase inhibitors. His innovative work has led to the filing of a patent that addresses critical challenges in RNA polymerase activity.
Latest Patents
Shahul Nilar holds a patent titled "Inhibitors for de novo-RNA polymerases and methods of identifying targets for same." This patent describes a polymerase inhibitor that features a first moiety coupled to a second moiety via an optional linker. The first moiety binds to an initiation nucleotide binding site of a polymerase, forming at least two hydrogen bonds with an RNA template strand associated with the polymerase. The second moiety comprises a compound that binds to a site proximal to the nucleotide binding site of the polymerase, thereby increasing the affinity of the polymerase inhibitor to the polymerase. This innovative approach has the potential to enhance the efficacy of treatments targeting RNA polymerase-related diseases.
Career Highlights
Throughout his career, Shahul Nilar has worked with prominent companies in the biotechnology sector. He has been associated with Ribapharm Inc. and Ardea Biosciences, Inc., where he contributed to various research and development projects. His expertise in polymerase inhibitors has positioned him as a valuable asset in these organizations.
Collaborations
Shahul Nilar has collaborated with several professionals in his field, including Nanhua Hugh Yao and Haoyun An. These collaborations have fostered a productive environment for innovation and have led to advancements in the understanding of polymerase inhibitors.
Conclusion
Shahul Nilar's contributions to the field of biotechnology, particularly through his patent on polymerase inhibitors, highlight his role as an innovator. His work continues to influence research and development in the industry, paving the way for future advancements in therapeutic applications.