This inventor holds 3 USPTO granted patents. Top assignees: Miles Inc., Miles Laboratories, Inc., Solvay Enzymes, Inc.. Active years: 1987-1996.
Company Filing History:
1 out of 540 
1 out of 504 
1 out of 17 Years Active: 1987-1996
Title: The Innovations of Sethuraman Subramanian
Introduction
Sethuraman Subramanian is an accomplished inventor based in Elkhart, IN (US). He holds a total of 3 patents that showcase his contributions to the field of protease research and purification methods. His work has significant implications for various industries, particularly in the development of detergent additives.
Latest Patents
One of his notable patents is focused on "Proteases of altered stability to autolytic degradation." This invention addresses the susceptibility of proteases to autolytic degradation. The method identifies susceptible autolysis sites that can be cleaved to produce discrete fragments. By chemically modifying the amino acids at or near the cleavage site or altering the DNA sequence through site-directed mutagenesis, Subramanian's invention aims to produce autolysis-stable proteases. This is particularly relevant for alkaline proteases, which are widely used as detergent additives. The stable alkaline proteases can be effectively utilized in liquid detergent formulations.
Another significant patent is for the "Purification of microbial rennet from Mucor miehei." This method involves the selective adsorption of microbial rennet present in the culture filtrate of Mucor miehei using a blue dye affinity ligand. The subsequent elution of the adsorbed microbial rennet results in a purified form, enhancing its usability in various applications.
Career Highlights
Throughout his career, Sethuraman Subramanian has worked with notable companies such as Miles Laboratories, Inc. and Miles Inc. His experience in these organizations has contributed to his expertise in the field of biochemistry and protease research.
Collaborations
He has collaborated with esteemed colleagues, including Josephine Grosch and John W. Shultz, further enriching his research and innovation endeavors.
Conclusion
Sethuraman Subramanian's contributions to the field of protease research and purification methods highlight his innovative spirit and dedication to advancing scientific knowledge. His patents not only demonstrate his expertise but also have practical applications that can benefit various industries.