Sergy Lemeshko

Title: Innovations by Sergy Lemeshko in Nucleic Acid Hybridization Devices

Introduction

Sergy Lemeshko is an accomplished inventor based in Houston, TX (US). He has made significant contributions to the field of biomolecular hybridization, particularly through his innovative patents. With a total of 2 patents, Lemeshko's work focuses on novel methods and devices for nucleic acid duplex formation on surfaces.

Latest Patents

Lemeshko's latest patents include groundbreaking technologies that enhance the efficiency of biomolecular hybridization. One of his notable inventions is a method and device based upon a novel form of nucleic acid duplex on a surface. This invention provides biomolecular hybridization devices that comprise a substrate with a permanently and covalently attached surface of functional groups. The devices utilize an adsorbed monolayer of unmodified, single-stranded oligonucleotides, which are effective in hybridizing to complementary single-stranded nucleic acids without dissociating from the surface. Another patent describes a simple method to fabricate DNA hybridization devices based on the adsorptive attachment of oligonucleotides to a positively charged surface. This method allows for the formation of a densely packed monolayer of oligonucleotide probes, which can hybridize with solution-state nucleic acid target strands.

Career Highlights

Throughout his career, Lemeshko has worked with various companies, including Genomics USA, Inc. His innovative approaches to nucleic acid hybridization have positioned him as a key figure in the field. His patents not only advance scientific understanding but also pave the way for practical applications in DNA microarrays and other nucleic acid analysis methods.

Collaborations

Lemeshko has collaborated with notable professionals in his field, including Michael E Hogan and Yuri Belosludtsev. These collaborations have further enriched his research and development efforts, leading to significant advancements in biomolecular technologies.

Conclusion

Sergy Lemeshko's contributions to the field of nucleic acid hybridization are noteworthy and impactful. His innovative patents and collaborative efforts continue to influence advancements in biomolecular research and applications.