Sergei Vladimirovich Mashko

Title: Innovations of Sergei Vladimirovich Mashko

Introduction

Sergei Vladimirovich Mashko is a prominent inventor based in Moscow, Russia. He has made significant contributions to the field of biotechnology, particularly in the area of bacterial fermentation. With a total of 14 patents to his name, his work has advanced the understanding and application of biosynthetic pathways.

Latest Patents

Among his latest patents is a method for producing a target substance by bacterial fermentation. This invention provides a method for producing substances such as amino acids, nucleosides, nucleotides, isoprenoids, and peptides through the fermentation of a genetically modified bacterium. The bacterium is designed to overexpress a gene encoding a protein with H-translocating membrane-bound pyrophosphatase activity, specifically the hppA gene or its variants. Another notable patent is a method for producing RNA. This method involves culturing a coryneform bacterium that has been modified to reduce the activity of ribonuclease III, allowing for the expression and accumulation of objective RNA within the cells.

Career Highlights

Throughout his career, Sergei has worked with various companies, including Ajinomoto Co., Ltd. His innovative approaches have led to advancements in the production of biochemicals and have had a lasting impact on the industry.

Collaborations

Sergei has collaborated with notable colleagues such as Vera Georgievna Doroshenko and Aleksandra Yurievna Skorokhodova. Their combined expertise has contributed to the success of their projects and innovations.

Conclusion

Sergei Vladimirovich Mashko's contributions to biotechnology through his patents and collaborations highlight his role as a leading inventor in the field. His work continues to influence advancements in bacterial fermentation and RNA production.