Company Filing History:
Years Active: 2024
Title: The Innovative Contributions of Serena Nik-zainal
Introduction
Serena Nik-zainal is a prominent inventor based in Hinxton, GB. She has made significant contributions to the field of genetics, particularly in the characterization of DNA samples. With a total of two patents to her name, her work is paving the way for advancements in cancer research and diagnostics.
Latest Patents
Serena's latest patents include a "Method of Characterizing a DNA Sample" and a "Method of Detecting a Mutational Signature in a Sample." The first patent provides methods for characterizing a DNA sample obtained from a tumor, producing an interpreted profile based on various tests. These tests include determining base substitution signatures, rearrangement signatures, insertion/deletion signatures, overall copy number profiles, and identifying putative driver mutations. The second patent focuses on detecting mutational signatures in a DNA sample, particularly those arising from rearrangements. This method involves computing the cosine similarity between rearrangement mutations and known rearrangement signatures, classifying them based on their characteristics.
Career Highlights
Serena Nik-zainal works at Genome Research Limited, where she applies her expertise in genetics to further research and innovation. Her work is instrumental in understanding the complexities of DNA and its implications in cancer.
Collaborations
Some of her notable coworkers include Dominik Glodzik and Mike Stratton, who collaborate with her on various research projects.
Conclusion
Serena Nik-zainal's innovative work in DNA characterization and mutational signature detection is making a significant impact in the field of genetics. Her contributions are essential for advancing cancer research and improving diagnostic methods.