Company Filing History:
Years Active: 2006
Title: Seetharaman Jayaraman: Innovator in Cyclosporin Analog Synthesis
Introduction
Seetharaman Jayaraman is a notable inventor based in Edmonton, Canada. He has made significant contributions to the field of pharmaceuticals, particularly in the synthesis of cyclosporin analogs. His work focuses on enhancing the efficacy and reducing the toxicity of these compounds.
Latest Patents
Jayaraman holds a patent for the "Synthesis of cyclosporin analogs." This invention is directed toward isomeric mixtures of cyclosporine analogues that are structurally similar to cyclosporine A. The mixtures he developed possess enhanced efficacy and reduced toxicity compared to individual isomers and other known cyclosporines. His work includes the synthesis of cis and trans-isomers of cyclosporin A analogs, specifically ISA247, and their derivatives. The synthesis employs stereoselective pathways, utilizing reactions such as the Wittig reaction and organometallic reagents.
Career Highlights
Jayaraman is associated with Isotechnika Inc., where he continues to innovate in the field of pharmaceutical chemistry. His research has led to advancements in the development of cyclosporin analogs that offer improved therapeutic profiles.
Collaborations
Some of his notable coworkers include Selvaraj A Naicker and Randall W Yatscoff, who have collaborated with him on various projects related to his research.
Conclusion
Seetharaman Jayaraman's contributions to the synthesis of cyclosporin analogs represent a significant advancement in pharmaceutical innovation. His work continues to impact the field positively, paving the way for more effective treatments.