This inventor holds 2 USPTO granted patents and 1 published patent application and 1 EPO patent. Top assignees: Adaptive Biotechnologies Corporation, Commissariat a L'energie Atomique Et Aux Energies Alternatives, Immunid. Active years: 2014-2023.
Company Filing History:


Years Active: 2014-2023
Title: Sébastien Weisbuch: Innovator in Immunological Diversity Analysis
Introduction
Sébastien Weisbuch is a notable inventor based in Villefontaine, France. He has made significant contributions to the field of immunology, particularly in the analysis of T and B lymphocyte diversity. With a total of 2 patents, his work has implications for disease diagnosis and treatment follow-up.
Latest Patents
Weisbuch's latest patents include innovative methods for studying V(D)J combinatory diversity. The first patent describes a method for analyzing the diversity of T and/or B lymphocytes in an individual. This method utilizes PCR multi-n-plexes to amplify genomic DNA fragments from a sample. It employs a combination of at least three primers that define at least two primer couples. Each couple includes a primer that hybridizes upstream and/or in a given V or D gene and another that hybridizes downstream and/or in a given J gene. This approach allows for the amplification of fragments characteristic of distinct V-J or D-J rearrangements. The applications of this method are particularly relevant in the treatment follow-up and diagnosis of certain diseases.
The second patent also focuses on measuring immunological diversity and evaluating treatment effects through V(D)J diversity analysis. Similar to the first, it involves the amplification of genomic DNA fragments using PCR multi-n-plexes. This method aims to provide insights into the immune response and the effectiveness of treatments.
Career Highlights
Throughout his career, Sébastien Weisbuch has worked with prominent organizations such as Immunid and the Commissariat à l'énergie atomique et aux énergies alternatives. His experience in these institutions has contributed to his expertise in immunological research and innovation.
Collaborations
One of his notable collaborators is Nicolas Pasqual, with whom he has worked on various projects related to immunology and patent development.
Conclusion
Sébastien Weisbuch's contributions to the field of immunology through his patents and collaborations highlight his role as an innovator in analyzing lymphocyte diversity. His work continues to impact the diagnosis and treatment of diseases, showcasing the importance of innovation in medical research.