Company Filing History:
Years Active: 2012-2020
Title: Innovations in Cancer Immunotherapy by Sathibalan Ponniah
Introduction
Sathibalan Ponniah is a prominent inventor based in Columbia, MD (US), known for his significant contributions to cancer immunotherapy. He holds a total of 10 patents, focusing on innovative vaccine compositions aimed at preventing breast cancer relapse and recurrence. His work is pivotal in advancing therapeutic options for patients in clinical remission.
Latest Patents
Ponniah's latest patents include a vaccine for the prevention of breast cancer relapse. This invention features methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER2/neu oncogene, E75. The methods involve administering an effective amount of a vaccine composition that includes a pharmaceutically acceptable carrier, an adjuvant such as recombinant human GM-CSF, and the E75 peptide at an optimized dose and schedule. Additionally, the methods comprise administering an annual or semi-annual booster vaccine dose to counteract declining E75-specific T cell immunity. Another notable patent is for a vaccine aimed at preventing breast cancer recurrence. This invention provides methods to induce and maintain a protective cytotoxic T-lymphocyte response to the GP2 peptide of the HER2/neu oncogene. The methods similarly involve administering a vaccine composition with a pharmaceutically acceptable carrier and GM-CSF as an adjuvant, along with periodic booster doses as needed.
Career Highlights
Ponniah is affiliated with the Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., where he continues to innovate in the field of cancer research. His work has garnered attention for its potential to improve patient outcomes and enhance the effectiveness of cancer treatments.
Collaborations
Some of his notable coworkers include George E Peoples and Catherine E Storrer, who contribute to the collaborative efforts in advancing cancer immunotherapy.
Conclusion
Sathibalan Ponniah's innovative work in developing vaccines for breast cancer demonstrates his commitment to improving therapeutic options for patients. His contributions are vital in the ongoing fight against cancer, showcasing the importance of research and innovation in medical science.