Location History:
- Heidelberg, DE (2016 - 2019)
- Augsburg, DE (2021)
- Ottowa, CA (2021)
Company Filing History:
2 out of 155 
1 out of 16 
1 out of 23 
Years Active: 2016-2021
Title: Sascha Bossow: Innovator in RNA Virus Research
Introduction
Sascha Bossow is a prominent inventor based in Heidelberg, Germany. He has made significant contributions to the field of virology, particularly in the development of RNA viruses for therapeutic applications. With a total of six patents to his name, Bossow's work focuses on innovative approaches to vaccine development and cancer treatment.
Latest Patents
One of Bossow's latest patents involves replication-deficient RNA viruses as vaccines. This invention describes a genome-replication-deficient and transcription-competent negative-strand RNA virus, which can be utilized for the expression of transgenes, especially in vaccine development. The recombinant Sendai virus he developed contains a viral genome with a mutation in the gene P, resulting in a loss of replication capacity while maintaining secondary transcription capabilities. This patent also includes a pharmaceutical composition that utilizes the Sendai virus, nucleocapsid, or viral genome as an active substance, particularly for medical use as a vaccine.
Another significant patent by Bossow relates to RNA viruses for immunovirotherapy. This invention features a recombinant virus from the Paramyxoviridae family, which includes at least one expressible polynucleotide encoding a secreted activator of the immune response. The patent outlines a method for treating cancer by administering this recombinant virus to subjects afflicted with the disease.
Career Highlights
Throughout his career, Sascha Bossow has worked with esteemed organizations, including the German Cancer Research Center (Deutsches Krebsforschungszentrum). His research has been pivotal in advancing the understanding of RNA viruses and their potential applications in medicine.
Collaborations
Bossow has collaborated with notable colleagues such as Wolfgang J. Neubert and Ulrich Manfred Lauer. These partnerships have contributed to the success and impact of his research endeavors.
Conclusion
Sascha Bossow's innovative work in RNA virus research has the potential to revolutionize vaccine development and cancer treatment. His contributions to the field are marked by a commitment to advancing medical science through groundbreaking inventions.