Company Filing History:
Years Active: 2014-2017
Title: Innovations in Cancer Treatment by Inventor Sarah Shuck
Introduction
Sarah Shuck is an accomplished inventor based in Nashville, TN (US). She has made significant contributions to the field of cancer research through her innovative work. With a total of 3 patents, her research focuses on targeting uncontrolled cell proliferation and enhancing the efficacy of chemotherapeutic agents.
Latest Patents
One of her latest patents involves materials and methods for inhibiting replication protein A and their uses in cancer treatment. This invention targets uncontrolled cell proliferation and resistance to DNA damaging chemotherapeutics. Replication Protein A is a crucial eukaryotic single-strand DNA binding protein that plays essential roles in genomic maintenance and stability. The reported small molecules inhibit the ssDNA binding activity of RPA, disrupting the eukaryotic cell cycle, inducing cytotoxicity, and increasing the effectiveness of chemotherapeutic agents. These findings provide new insights into the mechanisms of RPA-ssDNA interactions, representing a novel therapeutic strategy for cancer treatment.
Career Highlights
Sarah Shuck has established herself as a leading figure in her field. Her work at Indiana University has allowed her to collaborate with other experts and contribute to groundbreaking research.
Collaborations
One of her notable collaborators is John J Turchi, with whom she has worked on various projects related to cancer treatment and genomic stability.
Conclusion
Sarah Shuck's innovative research and patents are paving the way for new therapeutic strategies in cancer treatment. Her contributions are vital in the ongoing fight against cancer, showcasing the importance of targeted molecular approaches.