Company Filing History:
Years Active: 2025
Title: Sapir Margalit: Innovator in DNA Modification Quantification
Introduction
Sapir Margalit is a notable inventor based in Tel Aviv, Israel. She has made significant contributions to the field of genetic research, particularly in the area of DNA modification quantification. Her innovative work has led to the development of a unique patent that addresses critical challenges in epigenetic research.
Latest Patents
Margalit holds a patent for a "Multi-sample array chip for DNA modification quantification." This patent describes a method for detecting epigenetic DNA modifications. The method involves attaching a labeling agent selective for the DNA modification to the DNA. It also includes contacting an aqueous solution containing the DNA with at least one addressable region on a substrate's surface. This addressable region comprises a positively charged substance that facilitates the attachment of DNA to the surface, surrounded by a hydrophobic region. The process culminates in determining the amount of labeling agent present in the addressable region. Additionally, the patent outlines a kit that includes a substrate with discrete hydrophilic regions separated by a hydrophobic region, along with a labeling agent selective for an epigenetic DNA modification.
Career Highlights
Margalit is associated with Ramot at Tel Aviv University Ltd., where she continues to advance her research and innovation in the field of genetics. Her work is characterized by a commitment to enhancing the understanding of DNA modifications and their implications in various biological processes.
Collaborations
Throughout her career, Margalit has collaborated with esteemed colleagues, including Yuval Ebenstein and Shahar Zirkin. These collaborations have further enriched her research and contributed to the advancement of knowledge in the field.
Conclusion
Sapir Margalit stands out as an influential inventor in the realm of DNA modification quantification. Her innovative patent and ongoing research efforts reflect her dedication to advancing genetic science.