Company Filing History:
5 out of 21 
5 out of 832,680 Years Active: 2011-2018
Title: **Innovative Contributions of Sant K Srivastav in Nucleic Acid Chemistry**
Introduction
Sant K Srivastav, a notable inventor based in Burlington, MA, has made significant contributions to the field of nucleic acid chemistry. With a portfolio of eight patents, his work primarily focuses on enhancing the functionality and effectiveness of nucleosides and oligonucleotides, paving the way for advancements in biomedical research and diagnostics.
Latest Patents
Among his latest patents, one invention stands out: "Dithiolane functionalized nucleoside amidites and supports for stronger immobilization of bio-molecules on solid surfaces." This invention describes novel 1,2-dithiolane functionalized nucleoside phosphoramidites and corresponding solid supports, which are crucial for effective nucleic acid synthesis. These innovative derivatives allow for the introduction of reactive thiol groups at the 3′- or 5′-ends of oligonucleotides on various solid supports, including gold and silver. Additionally, his other patent relates to n-alkylated synthetic nucleosides of high regiospecific purity, which holds promise for the study of cytotoxic and mutagenic DNA damage and serves as diagnostic tools.
Career Highlights
Throughout his career, Sant has collaborated with prestigious companies in the biotechnology sector, including Chemgenes Corporation. His innovative work has not only extended his influence in nucleic acid chemistry but has also contributed to the broader scientific community through the publication and patenting of his groundbreaking inventions.
Collaborations
In addition to his work at Chemgenes Corporation, Sant K Srivastav has collaborated with esteemed colleagues such as Suresh C Srivastava and Stanley J Szymanski, Jr. These partnerships have facilitated the development of advanced nucleoside derivatives and have played a pivotal role in pushing the boundaries of current research methodologies.
Conclusion
Sant K Srivastav's contributions to the field of nucleic acid chemistry are extensive and impactful. His patents not only advance scientific knowledge but also provide essential tools for researchers working on DNA damage reversal and diagnostics. With his innovative approach and collaborative spirit, Sant continues to shape the landscape of biochemistry and molecular biology.
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