Location History:
- Edison, NJ (US) (2016 - 2020)
- Frederick, MD (US) (2007 - 2024)
- New York, NY (US) (2017 - 2024)
Company Filing History:
23 out of 68 
18 out of 1,187 
14 out of 28 
Years Active: 2007-2025
Title: **Innovative Contributions of Sanjay K Phogat in HIV Research**
Introduction
Sanjay K Phogat, based in Frederick, MD, is a prolific inventor with a remarkable portfolio of 24 patents. His work primarily focuses on advancements in the field of HIV research, specifically in the development of monoclonal antibodies that exhibit broad and potent neutralizing activities. His innovative contributions have the potential to significantly impact the prevention and treatment of HIV infection.
Latest Patents
Among his notable recent patents is his invention concerning monoclonal antibodies directed against trimeric forms of the HIV-1 envelope glycoprotein. This invention outlines a comprehensive method for obtaining broadly neutralizing antibodies (bNAbs). It includes screening memory B cell cultures from donor peripheral blood mononuclear cell (PBMC) samples for neutralization activity against various HIV-1 species. The process involves cloning memory B cells that demonstrate broad neutralizing activity and rescuing monoclonal antibodies from these cultures.
The resultant monoclonal antibodies are distinguished by their capacity to selectively bind to epitopes from envelope proteins in both native and monomeric forms. Additionally, they play a crucial role in inhibiting infections from multiple clades of HIV-1. Phogat’s patents also encompass compositions containing human monoclonal anti-HIV antibodies intended for prophylaxis, diagnosis, and treatment of HIV infection. Furthermore, his work provides innovative methods for generating such antibodies through immunization, utilizing epitopes from conserved regions within the variable loops of gp120.
Career Highlights
Sanjay K Phogat’s career is marked by significant contributions to HIV vaccine development. He has held key roles at prestigious research institutions, such as the International Aids Vaccine Initiative and The Scripps Research Institute. Throughout his career, he has dedicated his efforts to advancing the understanding and treatment of HIV, showcasing a solid commitment to public health and scientific progress.
Collaborations
Phogat has collaborated with esteemed colleagues in the field, including Dennis R. Burton and Wayne C. Koff. Their combined expertise has fostered innovative solutions and breakthroughs in HIV research, amplifying the impact of their collective work within the scientific community.
Conclusion
Sanjay K Phogat is a leading inventor in the realm of HIV research, with an extensive patent portfolio that reflects his dedication and innovation. His focus on developing broadly neutralizing antibodies represents a significant stride forward in combating HIV infection, promising a future where prevention and treatment strategies are more effective. Through collaboration with notable institutions and professionals, Phogat continues to contribute to advancements that could transform public health initiatives worldwide.