Company Filing History:
Years Active: 2006-2011
Title: Innovations by Inventor Sanjai Sharma in Immunomodulation
Introduction
Sanjai Sharma, an accomplished inventor based in La Jolla, California, has made significant contributions to the field of immunology through his innovative research and patented inventions. With a total of three patents to his name, Sharma's work focuses on chimeric nucleic acids and their applications in treating various human diseases.
Latest Patents
One of Sanjai Sharma's latest patents includes "Chimeric nucleic acids encoding polypeptides comprising CD70 and Fas ligand domains." This invention addresses the development of genes that encode accessory molecule ligands, which play a crucial role in immunomodulation, vaccination, and treatment of a range of human diseases, including malignancies and autoimmune disorders. The invention outlines the use of these ligands, composed of unique domains derived from the tumor necrosis factor family, that lead to enhanced stabilization of their activities. This stabilization is essential for their effectiveness in disease treatment, and the invention also details vectors for expressing the genes encoding these ligands.
Another notable patent is "Chimeric nucleic acids encoding polypeptides comprising CD154 and TNF-α." Similar to his previous work, this invention focuses on accessory molecule ligands and their potential in immunotherapeutic applications. The unique properties of the chimeric molecules in this patent again emphasize increased stability and efficacy in treating various diseases.
Career Highlights
Sanjai Sharma serves at the University of California, where he continues to push the boundaries of research in immunology. His groundbreaking inventions and patents not only contribute to academic knowledge but also present promising therapeutic avenues in clinical settings.
Collaborations
Sharma collaborates with esteemed colleagues, including Thomas James Kipps and Mark J Cantwell. These partnerships are vital in driving forward the innovative research and clinical applications of their inventions.
Conclusion
Sanjai Sharma's inventive contributions exemplify the impact of innovative thinking in addressing complex health challenges. His work in developing chimeric nucleic acids has opened new doors in immunomodulation, paving the way for advancements in treatment approaches for autoimmune diseases and malignancies.