Sandra Martina Van Ben Bosch

Title: Sandra Martina Van Ben Bosch: Innovator in Medical Imaging and Therapy

Introduction

Sandra Martina Van Ben Bosch is a prominent inventor based in Weert, Netherlands. She has made significant contributions to the field of medical imaging and therapeutics. Her innovative work focuses on developing advanced methods for targeted medical applications.

Latest Patents

Sandra holds a patent for a "Pretargeting kit for imaging or therapy comprising a trans-cyclooctene dienophile and a diene." This invention describes a pretargeting method and related kits for targeted medical imaging and/or therapeutics. The method utilizes abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention employs [4+2] inverse electron demand (retro) Diels-Alder chemistry to facilitate the coupling between a Pre-targeting Probe and an Effector Probe. One of these probes includes an electron-deficient tetrazine or other suitable diene, while the other features an E-cyclooctene with a flattened structure due to the positioning of at least two exocyclic bonds.

Career Highlights

Sandra is currently associated with Tagworks Pharmaceuticals B.V., where she continues to advance her research and development efforts. Her work is pivotal in enhancing the efficacy of medical imaging and therapeutic techniques.

Collaborations

Sandra collaborates with notable colleagues, including Marc Stefan Robillard and Johan Lub, contributing to a dynamic research environment that fosters innovation.

Conclusion

Sandra Martina Van Ben Bosch is a trailblazer in the realm of medical imaging and therapy, with her patent showcasing her innovative approach to enhancing targeted medical applications. Her contributions are vital to the ongoing advancements in this critical field.