Company Filing History:
Years Active: 2019-2020
Title: Innovations by Sandhya Sharma in Immunotherapy
Introduction
Sandhya Sharma is a prominent inventor based in Houston, Texas, known for her significant contributions to the field of immunotherapy. With a focus on developing methods for generating and expanding immune cells, she has made strides in addressing viral infections such as Epstein Barr Virus (EBV) and human papillomavirus (HPV). Her work has led to the filing of two patents that showcase her innovative approaches in this critical area of medical research.
Latest Patents
One of Sandhya Sharma's latest patents involves the generation of EBV-specific immune cells. This patent discloses methods for generating and expanding populations of immune cells that are specific for an EBV lytic antigen. The methods include stimulating immune cells by contacting peripheral blood mononuclear cells (PBMCs) with peptides corresponding to EBV lytic antigens or antigen presenting cells (APCs) that present these peptides. Additionally, the patent outlines the populations of immune cells that can be expanded using these methods and their potential uses in therapeutic applications.
Another significant patent focuses on the generation of HPV-specific T-cells. This invention details methods and compositions for immunotherapy targeting human papillomavirus infections and related diseases. The methods involve producing immune cells that specifically target antigens of HPV16 and/or HPV18, utilizing stimulation steps with IL-7 and IL-15, while avoiding IL-6 and/or IL-12. This innovative approach also includes specific embodiments that utilize stimulations in the presence of costimulatory cells and certain antigen presenting cells.
Career Highlights
Sandhya Sharma is affiliated with the Baylor College of Medicine, where she conducts her research and develops her innovative methods. Her work has garnered attention in the scientific community, contributing to advancements in immunotherapy and the treatment of viral infections.
Collaborations
Throughout her career, Sandhya has collaborated with esteemed colleagues, including Cliona M Rooney and Carlos A Ramos. These collaborations have further enhanced her research and the impact of her inventions in the field of immunotherapy.
Conclusion
Sandhya Sharma's innovative work in the field of immunotherapy, particularly her patents related to EBV and HPV, highlights her significant contributions to medical science. Her research continues to pave the way for new therapeutic approaches in combating viral infections.