Company Filing History:
Years Active: 2010
Title: Innovations of Samuel Tolley in Genetic Detection
Introduction
Samuel Tolley is an accomplished inventor based in Salt Lake City, Utah. He has made significant contributions to the field of genetic detection, particularly in the area of single nucleotide polymorphisms (SNPs). His work has implications for genetic research and diagnostics, showcasing the intersection of technology and biology.
Latest Patents
Samuel Tolley holds a patent for the "Detection of single nucleotide polymorphisms using planar waveguides." This patent describes methods and apparatus for detecting SNPs in genes of interest. The invention involves immobilizing a plurality of probes on a planar waveguide, which comprise sequences complementary to both a wildtype sequence of the gene and a known SNP sequence. A fluorescently-labeled analyte is flowed over the planar waveguide, and the binding between the labeled analyte and the probes results in a change in the fluorescence signal. The detection of the SNP is achieved by comparing the hybridization kinetics of the analyte with each of the probes. Additionally, a method of detecting SNPs in a gene of interest by sequencing through hybridization is also disclosed in the patent.
Career Highlights
Samuel Tolley is associated with the University of Utah Research Foundation, where he applies his expertise in genetic research. His innovative approach to SNP detection has positioned him as a notable figure in the field. His work not only advances scientific understanding but also has practical applications in medical diagnostics.
Collaborations
Samuel has collaborated with esteemed colleagues such as James N Herron and Hsu-Kun Wang. These collaborations have further enriched his research and contributed to the development of advanced genetic detection methods.
Conclusion
Samuel Tolley's contributions to the field of genetic detection through his innovative patent demonstrate the importance of technology in advancing our understanding of genetics. His work continues to influence research and applications in this critical area of science.
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