Company Filing History:
15 out of 69 
7 out of 3,539 
3 out of 13 
Years Active: 2007-2025
Title: The Innovative Contributions of Samir N Khleif
Introduction
Samir N Khleif, based in Silver Spring, MD, has established himself as a prominent inventor with a significant record of 22 patents. His groundbreaking work in immunology has the potential to influence the future of therapeutic treatments and vaccine development.
Latest Patents
Khleif's recent patents showcase his innovative approaches to immune response modulation. His first patent involves "Antibodies to programmed cell death protein 1". This invention presents antibodies and antigen-binding fragments that specifically bind to PD-1, promoting immune cell proliferation and activity instead of the traditional suppressive response associated with PD-1. By transmitting activating signals into the immune cells, these antibodies could enhance cytokine production and immune activation.
Additionally, his patent on "Methods of modulating immune responses with cationic lipid vaccine compositions" describes vaccine compositions combined with adjuvants and therapeutic factors. This innovation introduces methods to reduce immune suppressor cell populations and augment the immune response in mammals, ultimately contributing to better disease treatment methodologies.
Career Highlights
Throughout his career, Samir N Khleif has collaborated with esteemed organizations such as the Augusta University Research Institute and the United States Department of Health and Human Services. These affiliations highlight his commitment to advancing medical science and public health.
Collaborations
Khleif has worked alongside notable colleagues, including Mikayel Mkrtichyan and Iryna Lebedyeva. Their collaborative efforts amplify the impact of Khleif's research, fostering a culture of innovative thinking and shared knowledge in the field of immunology.
Conclusion
Samir N Khleif continues to push the boundaries of medical science with his innovative patents and collaborative spirit. His work promises to play a crucial role in shaping future therapies and vaccines, underscoring the importance of continued research in immune response modulation. The potential applications of his inventions could lead to significant advancements in treating various diseases, enhancing both patient outcomes and public health initiatives.