Company Filing History:
Years Active: 1997-1998
Title: The Innovative Contributions of Sambasiva Rao Ghanta in Pharmaceutical Patents
Introduction: Sambasiva Rao Ghanta, based in Centerville, OH, is a notable inventor in the pharmaceutical industry, holding three patents to his name. His specialization lies in the microencapsulation of water-insoluble NSAID drug materials, a process that has the potential to significantly enhance the efficacy of medicinal formulations.
Latest Patents: One of his most impactful patents is focused on the procedure for encapsulating ibuprofen. This innovation involves the preparation of individual taste-masked, high bioavailability microcapsules using microencapsulation techniques. The microcapsules contain more than 83% by weight of the NSAID drug material and are designed for incorporation into chewable tablets and liquid suspensions. The notable aspect of his work is the use of cellulose acetate phthalate and gelatin as microencapsulating materials, emphasizing the importance of controlling pH levels and using Hofmeister salts in the formulation process. This approach aims to produce taste-masked, water-insoluble NSAID drugs, facilitating better patient compliance.
Career Highlights: Sambasiva Rao Ghanta is currently employed at Eurand America, Inc., where his research and innovations in drug formulation have made significant contributions to the field of pharmacology. His work focuses on enhancing the delivery and bioavailability of various drugs, particularly NSAIDs like naproxen and ibuprofen. This endeavor highlights his commitment to improving therapeutic outcomes for patients.
Collaborations: Collaborating with esteemed colleagues such as Robert Edmon Guisinger and Marie Jean Bettman, Ghanta has been part of a team that emphasizes the importance of interdisciplinary collaboration in the realm of pharmaceutical research. These partnerships have fostered a robust exchange of ideas and expertise, enhancing the overall innovation process within the company.
Conclusion: Sambasiva Rao Ghanta's contributions to the field of pharmaceutical patents demonstrate his dedication to advancing drug formulation technologies. His innovative approach to microencapsulation not only enhances the efficacy of drugs but also underscores the importance of collaboration in the pursuit of medical advancements. His work serves as an inspiration for aspiring inventors and researchers in the pharmaceutical industry.