This inventor holds 2 USPTO granted patents. Top assignee: Florida International University. Active years: 2018-2023.
Company Filing History:
Years Active: 2018-2023
Title: Innovations by Samantha Dages
Introduction
Samantha Dages is an accomplished inventor based in Miami, Florida. She has made significant contributions to the field of biotechnology, particularly in the identification of gyrase inhibitors. With a total of two patents to her name, her work has the potential to impact various applications in medicine and research.
Latest Patents
Samantha's latest patents focus on materials and methods for identifying gyrase inhibitors. The disclosure describes the effects of transcription mediated from a promoter on the transcription mediated by divergently coupled supercoiling-sensitive promoters. Transcription initiated from a promoter inhibits transcription mediated by a specific supercoiling-sensitive promoter that is divergently coupled to the promoter. A gyrase inhibitor relieves this inhibition and substantially increases the transcription mediated by the specific supercoiling-sensitive promoter that is divergently coupled to another promoter. Accordingly, the invention pertains to a method for identifying a compound as a gyrase inhibitor or not a gyrase inhibitor based on differential expression of genes under the control of divergently coupled promoters in the presence of the compound. Another embodiment of the invention provides an assay for identifying one or more compounds from a library of compounds as a gyrase inhibitor. Additionally, polynucleotides and cells containing such polynucleotides that are suitable for carrying out the methods described herein are also provided.
Career Highlights
Samantha Dages is affiliated with Florida International University, where she continues her research and innovation in the field of biotechnology. Her work has garnered attention for its potential applications in drug discovery and genetic research.
Collaborations
Some of her notable coworkers include Fenfei Leng and Xiaoduo Zhi, who contribute to her research efforts and collaborative projects.
Conclusion
Samantha Dages is a pioneering inventor whose work on gyrase inhibitors showcases her commitment to advancing biotechnology. Her contributions are poised to make a significant impact in the field.