Company Filing History:
Years Active: 2003
Title: Salvaraj Naicker: Innovator in Immunomodulating Agents
Introduction
Salvaraj Naicker is a notable inventor based in Edmonton, Canada. He has made significant contributions to the field of immunology through his innovative work on cyclosporine derivatives. His research focuses on enhancing the efficacy and reducing the toxicity of immunomodulating agents.
Latest Patents
Naicker holds a patent for "Deuterated cyclosporine analogs and their use as immunomodulating agents." This patent describes cyclosporine derivatives that possess enhanced efficacy and reduced toxicity compared to naturally occurring and other known cyclosporins. The derivatives are produced through chemical and isotopic substitution of the cyclosporine A (CsA) molecule. Key modifications include chemical substitution and deuterium substitution at critical sites of metabolism, specifically amino acids 1, 4, and 9. The patent also outlines methods for producing these derivatives and achieving immunosuppression with reduced toxicity.
Career Highlights
Naicker is associated with Isotechnika Inc., where he has been instrumental in advancing research in immunomodulation. His work has contributed to the development of safer and more effective therapeutic options for patients requiring immunosuppression.
Collaborations
He has collaborated with notable colleagues, including Randall W. Yatscoff and Robert T. Foster, to further his research and development efforts in the field.
Conclusion
Salvaraj Naicker's innovative work in developing deuterated cyclosporine analogs represents a significant advancement in immunology. His contributions are paving the way for improved therapeutic strategies with reduced toxicity for patients.