Company Filing History:
Years Active: 2018
Title: Innovator Spotlight: Sally A. Kornbluth - Pioneering Cancer Therapeutics
Introduction: Sally A. Kornbluth is a distinguished inventor based in Durham, NC, known for her innovative contributions to the field of cancer therapeutics. With a strong academic background and a profound dedication to combating cancer, she has made significant advancements through her research and inventions.
Latest Patents: Dr. Kornbluth holds a notable patent titled "Methods of identifying and using MDM2 inhibitors." This patent details methods for treating subjects with cancer and screening for MDM2 inhibitors that show potential as effective cancer therapeutics. The patent addresses cancers that may show resistance to treatment with tyrosine kinase inhibitors, providing valuable insights into the use of MDM2 inhibitors in these situations. The methods described enable the treatment of cancers exhibiting elevated levels of MDM2, Mcl-1, or PP5, or decreased levels of Huwe1 or CAS. Additionally, these MDM2 inhibitors can be effective in treating these cancers alone or in combination with tyrosine kinase inhibitors, regardless of the p53 status of the cancer.
Career Highlights: Dr. Kornbluth is affiliated with Duke University, where she has made her mark as a researcher and innovator. Her dedication to understanding cancer biology and developing effective treatments has earned her recognition in the scientific community. The singular patent she holds reflects her expertise and commitment to advancing therapeutic options for patients diagnosed with cancer.
Collaborations: Throughout her career, Dr. Kornbluth has collaborated with esteemed colleagues, including Manabu Kurokawa and Neil Lee Spector. These partnerships have been instrumental in expanding her research endeavors and contributing to significant advancements in the innovative approaches to cancer treatment.
Conclusion: Sally A. Kornbluth continues to be an influential figure in the realm of cancer research and innovation. Her work on MDM2 inhibitors not only exemplifies her ingenuity as an inventor but also showcases her commitment to enhancing treatment options for cancer patients. As she continues her impactful work at Duke University, her contributions are expected to make a lasting difference in the fight against cancer.