Saeed Izadi

Title: Saeed Izadi and Antibody Electrostatics

Introduction

Saeed Izadi is an inventor associated with Genentech, Inc., in South San Francisco, California. His patent work concerns computational methods for modeling antibody electrostatics, a property relevant to the study and development of polypeptide therapeutics.

Latest Patents

Izadi is named on 1 patent: “Multipole Moment Based Coarse Grained Representation of Antibody Electrostatics.” The disclosure describes a method for representing an antibody’s electrostatic properties in a simplified model. It involves determining the antibody’s molecular multipole moments, selecting sites in a representation of the molecule, and assigning charges to those sites so their combined effects approximate the multipole moments. The model can then be used to simulate molecular interactions in solution, including interactions involving the modeled antibody.

Career Highlights

Izadi’s listed patent reflects work at the intersection of molecular modeling and therapeutic research. By providing a coarse-grained representation of antibody electrostatics, the disclosed approach aims to support simulations of molecular behavior that may inform the assessment of polypeptide properties.

Collaborations

Benjamin T. Walters is identified as Izadi’s coworker. The patent information provided does not specify their roles or describe a particular collaboration between them.

Conclusion

Saeed Izadi’s patent focuses on a computational approach to representing antibody electrostatics and simulating molecular interactions, connecting molecular modeling with research into potential polypeptide therapeutics.