This inventor holds 2 USPTO granted patents. Top assignee: Asahi Kasei Kogyo Kabushiki Kaisha. Active years: 1982.
Company Filing History:
Years Active: 1982
Title: The Innovations of Sadayuki Horiguchi
Introduction
Sadayuki Horiguchi is a notable inventor based in Fuji, Japan. He has made significant contributions to the field of biotechnology, particularly in the production of plasminogen activators. With a total of 2 patents to his name, Horiguchi's work has the potential to impact medical treatments and therapies.
Latest Patents
Horiguchi's latest patents focus on innovative processes for producing plasminogen activators. The first patent describes a method for enhancing the production of plasminogen activator from animal cells in a nutrient solution. By adding a large amount of fumaric acid, malic acid, succinic acid, and/or glycolic acid to the nutrient solution, he achieved a remarkable increase in the amount of plasminogen activator produced, ranging from 30% to 180%. The second patent outlines a process for producing a plasminogen activator with a molecular weight between 45,000 and 68,000. This activator is formed as a single fraction in human kidney or lung cells and can be efficiently separated and recovered without reducing its molecular weight. The method emphasizes maintaining suitable pH levels and dissolved oxygen concentrations during production, allowing for the activator to be formed over an extended period of more than 40 days.
Career Highlights
Horiguchi is associated with Asahi Kasei Kogyo Kabushiki Kaisha, a prominent company in the chemical and pharmaceutical industry. His work there has been instrumental in advancing biotechnological processes and enhancing the efficiency of plasminogen activator production.
Collaborations
Horiguchi has collaborated with notable coworkers, including Akio Hasegawa and Mitsuru Shibukawa. Their combined expertise has contributed to the successful development of innovative solutions in their field.
Conclusion
Sadayuki Horiguchi's contributions to biotechnology, particularly in the production of plasminogen activators, showcase his innovative spirit and dedication to advancing medical science. His patents reflect a commitment to improving therapeutic processes, which may lead to significant advancements in healthcare.