Company Filing History:
Years Active: 2019
Title: Sabrina Kneissl: Innovator in Gene Transfer Technologies
Introduction
Sabrina Kneissl is a prominent inventor based in Darmstadt, Germany. She has made significant contributions to the field of gene transfer technologies, particularly through her innovative work on retroviral vectors. Her research has the potential to impact various applications in gene therapy and biotechnology.
Latest Patents
Sabrina Kneissl holds a patent for her invention titled "Pseudotyping of retroviral vectors, methods for production and use thereof for targeted gene transfer and high throughput screening." This invention relates to the pseudotyping of retroviral vectors with heterologous envelope proteins derived from the Paramyxoviridae family. The invention is based on the surprising finding that incorporating F and H proteins with truncated cytoplasmic tails into lentiviral vector particles enhances the transduction of cells. Furthermore, these pseudotyped vector particles enable targeted gene transfer into specific cell types by modifying a mutated and truncated H protein with a single-chain antibody or ligand directed against a cell surface marker of the target cell. She has 1 patent to her name.
Career Highlights
Sabrina Kneissl is associated with the Paul-Ehrlich-Institut, where she contributes to advancing research in the field of gene therapy. Her work is characterized by a commitment to innovation and excellence in scientific research.
Collaborations
Throughout her career, Sabrina has collaborated with notable colleagues, including Christian Buchholz and Klaus Cichutek. These collaborations have further enriched her research and contributed to the advancement of gene transfer technologies.
Conclusion
Sabrina Kneissl is a trailblazer in the field of gene transfer, with her innovative patent paving the way for future advancements in targeted gene therapy. Her contributions are vital to the ongoing evolution of biotechnology and medicine.