San Diego, CA, United States of America

Ryan Shenvi

USPTO Granted Patents = 3 

Average Co-Inventor Count = 4.6

ph-index = 1

Forward Citations = 12(Granted Patents)


Company Filing History:


Years Active: 2014-2022

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3 patents (USPTO):Explore Patents

Title: Ryan Shenvi: Innovator in Kappa-Opioid Modulation

Introduction

Ryan Shenvi is a prominent inventor based in San Diego, CA. He has made significant contributions to the field of medicinal chemistry, particularly in the development of novel compounds for therapeutic use. With a total of 3 patents, his work focuses on innovative solutions for medical conditions that require modulation of the kappa-opioid receptor.

Latest Patents

One of Ryan Shenvi's latest patents is the synthesis of 20-nor-salvinorin A. This invention provides an analog of the kappa-opioid agonist salvinorin A, which is an active kappa-opioid modulator. The 20-nor-salvinorin A can be utilized for treating various medical conditions, including pain, pruritis, depression, and inflammation. It is particularly noteworthy for being less addictive compared to traditional mu-opioid receptor agonists and demonstrates greater stability in vivo than its parent compound, salvinorin A. Additionally, the patent includes synthetic intermediates and procedures for the preparation of 20-nor-salvinorin A.

Another significant patent involves short syntheses of (−)-picrotoxinin and related compounds. This disclosure outlines concise processes for producing (−)-picrotoxinin and 5-methyl-picrotoxinin, along with their pharmaceutical compositions and methods of use for inhibiting GABA receptors.

Career Highlights

Ryan Shenvi has worked at The Scripps Research Institute, where he has been involved in groundbreaking research and development. His work at this prestigious institution has allowed him to explore innovative approaches to drug design and synthesis.

Collaborations

Throughout his career, Ryan has collaborated with notable colleagues, including Carlos A Guerrero and Jun Shi. These collaborations have contributed to the advancement of his research and the successful development of his patented inventions.

Conclusion

Ryan Shenvi is a distinguished inventor whose work in kappa-opioid modulation has the potential to transform therapeutic approaches for various medical conditions. His innovative patents and contributions to medicinal chemistry highlight his commitment to advancing healthcare solutions.

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