Company Filing History:
Years Active: 2017-2020
Title: Innovations of Ryan Duggan in Quantitative Immunoassays
Introduction
Ryan Duggan is an accomplished inventor based in Chicago, IL. He has made significant contributions to the field of quantitative immunoassays, holding a total of 2 patents. His work focuses on advanced methods and compositions that enhance the accuracy and efficiency of immunoassays.
Latest Patents
Duggan's latest patents include innovative techniques for oligonucleotide-mediated quantitative multiplexed immunoassays. These methods utilize ligand-conjugated probes to label samples, while ligand-surfaced microspheres serve as quantitative reference standards. One embodiment of his work involves a method of quantitative flow cytometry where oligonucleotides act as ligands. In this process, a sample containing one or more cells is treated with a hybridized antibody::fluorophore labeled targeting construct to label the cells for analysis. The labeled cells are then examined using a flow cytometer, which also analyzes a population of quantitative labeled oligospheres. This analysis creates a standard curve of cytometer intensity versus molecules of fluorescent label per oligosphere event. The established trendline is crucial for determining the molecules of fluorescent label per cellular event for antigen-positive cell populations. Ultimately, this allows for the quantification of Antibody Binding per Cell (ABC) based on the molecules of fluorescent label per cell.
Career Highlights
Ryan Duggan is affiliated with The University of Chicago, where he continues to advance his research in immunoassays. His innovative approaches have garnered attention in the scientific community, contributing to the development of more precise diagnostic tools.
Collaborations
Duggan collaborates with notable colleagues, including Amy Flor and Stephen Joseph Kron. Their combined expertise enhances the research and development of new methodologies in the field.
Conclusion
Ryan Duggan's contributions to quantitative immunoassays exemplify the impact of innovative research in the medical and scientific fields. His patents reflect a commitment to improving diagnostic techniques, ultimately benefiting healthcare and research.