Ruoyu Zhang

Title: Innovations by Ruoyu Zhang in Methylation Analysis

Introduction

Ruoyu Zhang is an accomplished inventor based in Ithaca, NY, known for his significant contributions to the field of genomic research. His work primarily focuses on distinguishing methylation levels in complex biological samples, which has important implications for cancer research and diagnostics.

Latest Patents

Ruoyu Zhang holds a patent for a method that distinguishes aberrant methylation levels for DNA from a first cell type. This innovative method includes several steps: providing a test data set with methylation states from test genomic DNA, comparing these states to reference genomic DNA, determining the methylation difference, and weighting this difference by coverage at each site. This process results in an aggregate coverage-weighted normalized methylation difference score. Additionally, his methods are sensitive enough to distinguish cancer cells from normal cells and classify different cancer types based on their tissues of origin.

Career Highlights

Ruoyu Zhang is currently employed at Illumina Corporation, a leading company in the field of genomics. His work at Illumina has allowed him to further develop his innovative methods and contribute to advancements in genomic technologies.

Collaborations

Ruoyu Zhang has collaborated with notable colleagues, including Jonathan Toung and Li Liu, to enhance the research and development of genomic analysis techniques.

Conclusion

Ruoyu Zhang's innovative work in methylation analysis represents a significant advancement in genomic research, particularly in the context of cancer diagnostics. His contributions continue to influence the field and pave the way for future discoveries.