Company Filing History:
Years Active: 1990-1993
Title: **Rudolf F. Bliem: Innovator in Animal Cell Culture Technology**
Introduction
Rudolf F. Bliem, based in Castro Valley, CA, is a notable inventor with a focus on advancements in the field of animal cell culture technologies. With a total of 4 patents to his name, Bliem has made significant contributions that help in the recovery of secreted proteins. His innovative approaches are designed to enhance scalability and efficiency in in vitro cultures.
Latest Patents
Bliem's latest inventions include:
1. **Apparatus for Culturing Animal Cells**: This apparatus is designed for the in vitro culture of animal cells, aimed at recovering secreted proteins of interest. It features a housed arrangement of culture subunits that contain a packed bed of carrier particles. Each subunit is fed in parallel from a common culture medium source, while the spent culture fluid is directed to a common spent fluid conduit. The system allows for scalable protein production by adding or removing culture subunits or adjusting the carrier particle volume, all while maintaining a consistent packed bed height.
2. **Method for Culturing Animal Cells**: This method utilizes the previously mentioned apparatus for in vitro culture to recover secreted proteins effectively. Similar to the apparatus, it affords scalable options for protein production by adjusting the number of culture subunits and the volume of carrier particles while maintaining a stable packed bed height.
Career Highlights
Rudolf F. Bliem currently works at Baxter International Inc., a global leader in healthcare. His role involves leveraging his expertise in cell culture technologies to innovate and improve methodologies that can lead to better yields of proteins used in various medical applications.
Collaborations
Throughout his career, Bliem has collaborated with esteemed colleagues, including Robert V. Oakley and Van C. Taiariol. These professional relationships foster an environment of creativity and collective problem-solving that drives the advancement of their shared goals in biotechnology.
Conclusion
Rudolf F. Bliem's inventions in cell culture technology exemplify the spirit of innovation in addressing complex challenges within the field. His patents reflect a commitment to enhancing in vitro practices and improving outcomes in protein recovery, thereby contributing significantly to advancements in biotechnology.