Ross W Cheloha

Title: The Innovative Contributions of Ross W. Cheloha

Introduction

Ross W. Cheloha is a notable inventor based in Madison, WI (US), recognized for his significant contributions to the field of biochemistry and pharmacology. With a total of 2 patents, Cheloha has made strides in developing engineered ligands and polypeptide analogs that have potential therapeutic applications.

Latest Patents

Cheloha's latest patents include "Engineered ligands and uses thereof," which describes engineered ligands that bind to cell surface receptors, such as GPCRs, with improved affinity, potency, and specificity. This innovation enhances the effectiveness of sub-optimal ligands by conjugating them to targeting molecules that bind to specific epitopes on the receptor. Another significant patent is "Alpha-/beta-polypeptide analogs of parathyroid hormone (PTH) and method of using same." This patent details polypeptide analogs of PTH that incorporate non-adjacent β-amino acid residues, offering new pharmaceutical compositions for treating hypoparathyroidism.

Career Highlights

Throughout his career, Cheloha has worked with esteemed organizations, including the General Hospital Corporation and Children's Medical Center Corporation. His work in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Some of Cheloha's notable coworkers include Thomas J. Gardella and Hidde L. Ploegh. Their collaborative efforts have further advanced the research and development of innovative therapeutic solutions.

Conclusion

Ross W. Cheloha's contributions to the field of biochemistry through his patents and collaborations highlight his role as a significant inventor. His work continues to pave the way for advancements in medical treatments and therapies.