Ross B Fulton

Title: Innovations by Ross B Fulton in Lipid Nanoparticle Technology

Introduction

Ross B Fulton is an accomplished inventor based in Southborough, MA, with a focus on advancements in lipid nanoparticle technology. He holds two patents that contribute significantly to the field of therapeutic nucleic acid delivery. His work aims to enhance the efficacy and safety of nanoparticle formulations used in medical applications.

Latest Patents

Fulton's latest patents include innovative compositions of ionizable lipid nanoparticles designed for the delivery of therapeutic nucleic acids to cells. One of his patents details the engineering of cationic ionizable lipids that exhibit improved stability against oxidative degradation while maintaining high transfection activity in cells. These biodegradable lipids enhance the tolerability of nanoparticles in vivo. Another patent focuses on the inclusion of anionic phospholipids, such as phosphatidylserine and phosphatidylglycerol, which significantly increase transfection efficiency in human dendritic cells. The incorporation of mono-unsaturated alkyl chain analogs and ammonium salts of phosphatidylserine further optimizes the production of PS-targeted lipid nanoparticles.

Career Highlights

Fulton is currently associated with Akagera Medicines, Inc., where he continues to innovate in the field of drug delivery systems. His contributions have been pivotal in advancing the understanding and application of lipid nanoparticles in therapeutic contexts.

Collaborations

Fulton has collaborated with notable colleagues, including Daryl C Drummond and Dmitri B Kirpotin, to further enhance the research and development of lipid nanoparticle technologies.

Conclusion

Ross B Fulton is a key figure in the development of lipid nanoparticles for nucleic acid delivery, with patents that reflect his commitment to improving therapeutic outcomes. His work continues to influence the field of medical research and drug delivery systems.